{"id":9686,"date":"2022-06-22T11:00:29","date_gmt":"2022-06-22T10:00:29","guid":{"rendered":"https:\/\/ring20researchsupport.co.uk\/?p=9686"},"modified":"2023-02-10T08:54:38","modified_gmt":"2023-02-10T08:54:38","slug":"impact_of_r20","status":"publish","type":"post","link":"https:\/\/ring20researchsupport.co.uk\/ja\/2022\/06\/impact_of_r20\/","title":{"rendered":"\u30ea\u30f3\u30b0\u67d3\u8272\u4f53 20 \u75c7\u5019\u7fa4\u306e\u5f71\u97ff\u306e\u30ec\u30d3\u30e5\u30fc"},"content":{"rendered":"
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Ring20 (\u6148\u5584\u56e3\u4f53) \u306f\u60a3\u8005\u306e\u751f\u6d3b\u3092\u6539\u5584\u3057\u3001r(20) \u75c7\u5019\u7fa4\u306e\u5c06\u6765\u306e\u7814\u7a76\u306b\u4e0d\u53ef\u6b20\u3067\u3059\u3002<\/p><\/blockquote>

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r(20)\u75c7\u5019\u7fa4\u306b\u95a2\u3059\u308b\u7814\u7a76\u306f\u304b\u306a\u308a\u307e\u3070\u3089\u3067\u3042\u308a\u3001\u3053\u306e\u72b6\u614b\u304c\u975e\u5e38\u306b\u307e\u308c\u3067\u3042\u308b\u305f\u3081\u3001\u7814\u7a76\u3067\u306f\u5927\u304d\u306a\u30b5\u30f3\u30d7\u30eb\u3092\u8abf\u3079\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u305b\u3093.\u3057\u304b\u3057\u3001\u5f71\u97ff\u3092\u53d7\u3051\u305f\u7d30\u80de\u306e\u6570\u3068\u3066\u3093\u304b\u3093\u306e\u767a\u75c7\u5e74\u9f62\u3068\u306e\u9593\u306b\u95a2\u4fc2\u304c\u3042\u308b\u53ef\u80fd\u6027\u3092\u6307\u6458\u3059\u308b\u4eba\u3082\u3044\u307e\u3059 (Elens et al., 2012) \u304a\u3088\u3073 (Giardino et al., 2010)\u3002 Daber\u7b49\u3002 (2012) \u306f\u3001\u6b21\u4e16\u4ee3\u306e DNA \u304a\u3088\u3073 RNA \u914d\u5217\u6c7a\u5b9a\u306b\u95a2\u9023\u3059\u308b\u65b0\u3057\u3044\u6280\u8853\u304c\u3001\u6b63\u78ba\u306a\u74b0\u72b6\u67d3\u8272\u4f53\u69cb\u9020\u306e\u89e3\u660e\u306b\u6709\u671b\u3067\u3042\u308b\u3068\u8003\u3048\u3066\u3044\u307e\u3059\u3002 r(20) \u75c7\u5019\u7fa4\u306e\u60a3\u8005\u3068\u305d\u306e\u5bb6\u65cf\u306f\u3001\u5fc5\u7136\u7684\u306b\u5f7c\u3089\u306e\u533b\u7642\u306b\u975e\u5e38\u306b\u71b1\u5fc3\u3067\u77e5\u8b58\u304c\u8c4a\u5bcc\u3067\u3042\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059 (Donald et al., 2020)\u3002\u5f7c\u3089\u306e\u307b\u3068\u3093\u3069\u306f\u7814\u7a76\u3078\u306e\u53c2\u52a0\u3092\u671b\u3093\u3067\u3044\u307e\u3059\u304c\u3001\u8907\u96d1\u306a\u30b1\u30a2\u30d7\u30ed\u30bb\u30b9\u306b\u9069\u5408\u3059\u308b\u306b\u306f\u3001\u5b9f\u7528\u7684\u304b\u3064\u73fe\u5b9f\u7684\u3067\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093.\u3066\u3093\u304b\u3093\u30b0\u30eb\u30fc\u30d7\u3068\u5354\u529b\u3059\u308b\u3053\u3068\u3067\u3001\u52df\u96c6\u3068\u7814\u7a76\u306e\u5f71\u97ff\u304c\u5927\u5e45\u306b\u6539\u5584\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001Ring20 \u306e\u3088\u3046\u306a\u6148\u5584\u56e3\u4f53\u306f\u3001\u60a3\u8005\u3068\u81e8\u5e8a\u533b\u3092\u3055\u3089\u306a\u308b\u7814\u7a76\u306b\u7d50\u3073\u4ed8\u3051\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\u3002 Ring20 \u306f\u3001\u751f\u30c7\u30fc\u30bf\u3068\u7814\u7a76\u30b0\u30eb\u30fc\u30d7\u3092\u63d0\u4f9b\u3057\u3001\u60a3\u8005\u30b0\u30eb\u30fc\u30d7\u3068\u533b\u7642\u5c02\u9580\u5bb6\u306e\u9593\u306b\u5207\u671b\u3055\u308c\u3066\u3044\u305f\u5171\u540c\u4f53\u306e\u611f\u899a\u3092\u751f\u307f\u51fa\u3059\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u7814\u7a76\u306b\u3088\u308b\u3068\u3001r(20) \u75c7\u5019\u7fa4\u306e\u30d6\u30ec\u30fc\u30af\u30b9\u30eb\u30fc\u306b\u8fd1\u3065\u3044\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u3066\u3044\u307e\u3059\u304c\u3001\u53c2\u52a0\u8005\u304c\u4e0d\u8db3\u3057\u3066\u3044\u308b\u305f\u3081\u3086\u3063\u304f\u308a\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u3089\u306e\u7814\u7a76\u3092\u652f\u63f4\u3059\u308b Ring20 \u306e\u3088\u3046\u306a\u6148\u5584\u56e3\u4f53\u304c\u306a\u3051\u308c\u3070\u3001\u4f55\u767e\u4eba\u3082\u306e\u4eba\u3005\u304c\u5fc5\u8981\u4ee5\u4e0a\u306b\u9577\u304f r(20) \u75c7\u5019\u7fa4\u306e\u60aa\u5f71\u97ff\u3092\u53d7\u3051\u308b\u3053\u3068\u306b\u306a\u308a\u307e\u3059\u3002
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\u65b9\u6cd5\u8ad6 <\/b>
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4) \u5bb6\u65cf\u4f1a\u8b70\u30a4\u30d9\u30f3\u30c8\u3001\u4f1a\u8b70\u3001\u5c02\u9580\u5bb6\u304b\u3089\u306e\u30d2\u30a2\u30ea\u30f3\u30b0\u3002
5) \u6bce\u6708\u306e\u30cb\u30e5\u30fc\u30b9\u30ec\u30bf\u30fc\u3002
6) \u30b3\u30fc\u30d2\u30fc\u3068\u30c1\u30e3\u30c3\u30c8 \u30bd\u30fc\u30b7\u30e3\u30eb\u3002
7) Ring20\u60c5\u5831\u30b5\u30a4\u30c8
8) \u30a6\u30a7\u30eb\u30d3\u30fc\u30a4\u30f3\u30b0 \u30ef\u30fc\u30af\u30b7\u30e7\u30c3\u30d7\u3002
9) \u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u306e\u4e00\u54e1\u3067\u3042\u308b\u3053\u3068\u3001\u5b64\u72ec\u3092\u611f\u3058\u306a\u3044\u3053\u3068
10) \u60a3\u8005\u60c5\u5831\u6f2b\u753b\u3002<\/p>

\u7d50\u679c<\/b>
\u88681\u3002
\u4ee5\u4e0b\u306e\u8868\u306f\u3001\u5404\u9805\u76ee\u306e\u5f97\u7968\u6570\u3068\u53c2\u52a0\u8005\u6570\u306b\u5bfe\u3059\u308b\u5f97\u7968\u7387\u3067\u3059\u3002<\/p>

\u30a2\u30a4\u30c6\u30e0<\/strong><\/p><\/td>

Q1<\/strong><\/p><\/td>

Q2<\/strong><\/p><\/td>

Q3<\/strong><\/p><\/td>

Q4<\/strong><\/p><\/td>

Q5<\/strong><\/p><\/td>

Q6<\/strong><\/p><\/td>

Q7<\/strong><\/p><\/td>

Q8<\/strong><\/p><\/td>

Q9<\/strong><\/p><\/td>

Q10<\/strong><\/p><\/td><\/tr>

\u00a0<\/strong><\/p>

\u6295\u7968\u6570<\/strong><\/p><\/td>

37<\/p><\/td>

19<\/p><\/td>

31<\/p><\/td>

24<\/p><\/td>

25<\/p><\/td>

23<\/p><\/td>

26<\/p><\/td>

21<\/p><\/td>

35<\/p><\/td>

18<\/p><\/td><\/tr>

\u00a0<\/strong><\/p>

\u30d1\u30fc\u30bb\u30f3\u30c6\u30fc\u30b8<\/strong><\/p>

\u00a0<\/strong><\/p><\/td>

84<\/p><\/td>

43<\/p><\/td>

70<\/p><\/td>

55<\/p><\/td>

57<\/p><\/td>

52<\/p><\/td>

59<\/p>

\u00a0<\/p><\/td>

48<\/p><\/td>

80<\/p>

\u00a0<\/p><\/td>

40<\/p><\/td><\/tr><\/tbody><\/table>

\u30b0\u30e9\u30d5 1\u3002
\u4ee5\u4e0b\u306e\u30b0\u30e9\u30d5\u306f\u3001\u8868 1 \u306e\u8abf\u67fb\u7d50\u679c\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>

\"\"<\/p>

\u30b0\u30e9\u30d5 2\u3002
\u4ee5\u4e0b\u306e\u30b0\u30e9\u30d5\u306f\u3001\u5404\u53c2\u52a0\u8005\u306e\u51fa\u8eab\u5730\u3092\u30d1\u30fc\u30bb\u30f3\u30c6\u30fc\u30b8\u3067\u793a\u3057\u3066\u3044\u307e\u3059\u3002<\/p>

\"\"<\/p>

\u30b3\u30e1\u30f3\u30c8 \u30bb\u30af\u30b7\u30e7\u30f3 1\u3002<\/b>
\u53c2\u52a0\u8005 A (PA) \u2013
\u300c\u79c1\u305f\u3061\u306f\u975e\u5e38\u306b\u5c0f\u3055\u306a\u30b0\u30eb\u30fc\u30d7\u3067\u3042\u308a\u3001\u305d\u3053\u306b\u306f\u591a\u304f\u306e\u60c5\u5831\u3084\u30b5\u30dd\u30fc\u30c8\u304c\u306a\u3044\u305f\u3081\u3001\u3053\u308c\u3089\u3059\u3079\u3066\u304c\u79c1\u305f\u3061\u306e\u30ea\u30f3\u30b0 20 \u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u5f79\u7acb\u3064\u3068\u611f\u3058\u3066\u3044\u307e\u3059 .\u3069\u3093\u306a\u65b0\u3057\u3044\u7814\u7a76\u304c\u79c1\u305f\u3061\u306b\u3084\u3063\u3066\u304f\u308b\u304b\u3092\u898b\u308b\u305f\u3081\u306b\u300d
PB \u2013
\u300cR(20)\u306e\u5f71\u97ff\u3092\u53d7\u3051\u305f\u6700\u65b0\u306e\u5bb6\u65cf\u306e 1 \u4eba\u3068\u3057\u3066\u3001\u3053\u306e\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u3068\u30b5\u30dd\u30fc\u30c8\u3092\u898b\u3064\u3051\u3066\u3001\u79c1\u305f\u3061\u304c\u4e00\u4eba\u3067\u306f\u306a\u3044\u3053\u3068\u3092\u77e5\u3063\u3066\u3001\u3068\u3066\u3082\u611f\u8b1d\u3057\u3066\u3044\u307e\u3059\u3002\u79c1\u306f\u7814\u7a76\u3055\u308c\u305f\u79d1\u5b66\u7684\u60c5\u5831\u3060\u3051\u3067\u306a\u304f\u3001\u4ed6\u306e\u5bb6\u65cf\u304b\u3089\u306e\u672c\u5f53\u306e\u8a71\u3082\u3068\u3066\u3082\u5927\u5207\u306b\u3057\u3066\u3044\u307e\u3059.\u53cb\u4eba\u3001\u5bb6\u65cf\u3001\u6559\u80b2\u8005\u3001\u533b\u7642\u5c02\u9580\u5bb6\u304c\u8cea\u554f\u3092\u3059\u308b\u3068\u304d\u3001\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8\u3078\u306e\u30ea\u30f3\u30af\u3092\u9001\u308b\u3053\u3068\u306f\u975e\u5e38\u306b\u5f79\u306b\u7acb\u3061\u307e\u3057\u305f\u3002\u300d
\u30d1\u30bd\u30b3\u30f3 \u2013
\u300c\u79c1\u305f\u3061\u306f\u4e00\u4eba\u3067\u306f\u306a\u3044\u3053\u3068\u3092\u77e5\u308a\u305f\u3044\u3067\u3059\u3002\u3042\u306a\u305f\u304c\u3068\u3066\u3082\u5b64\u7acb\u3057\u3066\u7d76\u671b\u3057\u3066\u3044\u308b\u3068\u611f\u3058\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3088\u3046\u306b\u3002\u533b\u8005\u304c\u79c1\u305f\u3061\u306b\u63d0\u4f9b\u3067\u304d\u308b\u3082\u306e\u306f\u307b\u3068\u3093\u3069\u306a\u3044\u306e\u3067\u3001Unravel \u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u306e\u305f\u3081\u306b\u79c1\u305f\u3061\u304c\u63a2\u3057\u51fa\u3055\u308c\u305f\u306e\u306f\u7d20\u6674\u3089\u3057\u3044\u3053\u3068\u3067\u3057\u305f.\u79c1\u305f\u3061 (\u89aa\u3001\u4ecb\u8b77\u8005\u3001\u60a3\u8005) \u306f\u7686\u3001\u4e00\u7dd2\u306b\u3053\u306e\u554f\u984c\u306b\u53d6\u308a\u7d44\u3093\u3067\u304a\u308a\u3001Ring 20 \u306e\u60a3\u8005\u30b5\u30dd\u30fc\u30c8\u306f\u79c1\u305f\u3061\u306b\u3068\u3063\u3066\u304b\u3051\u304c\u3048\u306e\u306a\u3044\u3082\u306e\u3067\u3059\u3002\u79c1\u305f\u3061\u306e\u5177\u4f53\u7684\u306a\u554f\u984c\u306b\u3064\u3044\u3066\u3001\u3053\u308c\u307b\u3069\u8a73\u3057\u3044\u60c5\u5831\u3092\u63d0\u4f9b\u3057\u3066\u3044\u308b\u3068\u3053\u308d\u306f\u4ed6\u306b\u3042\u308a\u307e\u305b\u3093\u3002\u300d
PD \u2013
\u300c\u3053\u308c\u3089\u306e\u3059\u3079\u3066\u306e\u70b9\u3067\u3068\u3066\u3082\u91cd\u8981\u3060\u3068\u611f\u3058\u3066\u3044\u307e\u3059.\u6642\u3005\u3001\u79c1\u305f\u3061\u306f\u3068\u3066\u3082\u843d\u3061\u8fbc\u3093\u3067\u5b64\u72ec\u306b\u611f\u3058\u307e\u3059\u304c\u3001\u975e\u5e38\u306b\u4f3c\u305f\u72b6\u6cc1\u306b\u3042\u308b\u5bb6\u65cf\u3068\u3064\u306a\u304c\u308b\u3053\u3068\u3067\u3001\u79c1\u305f\u3061\u306f\u4e00\u7dd2\u306b\u3044\u308b\u3068\u611f\u3058\u3001\u304a\u4e92\u3044\u3092\u652f\u3048\u5408\u3046\u3053\u3068\u304c\u3067\u304d\u307e\u3059.\u300d<\/p>

\u8a0e\u8ad6<\/b>
\u7d50\u679c\u3068\u30b3\u30e1\u30f3\u30c8\u304b\u3089\u308f\u304b\u308b\u3088\u3046\u306b\u3001\u53c2\u52a0\u8005\u306f Ring20 \u304c\u63d0\u4f9b\u3059\u308b\u30b5\u30dd\u30fc\u30c8\u304b\u3089\u5927\u304d\u306a\u6069\u6075\u3092\u53d7\u3051\u3066\u3044\u307e\u3059\u3002\u8868 1 \u306b\u793a\u3059\u3088\u3046\u306b\u300144 \u4eba\u306e\u53c2\u52a0\u8005\u306e\u534a\u6570\u4ee5\u4e0a\u304c\u3001\u30ea\u30b9\u30c8\u3055\u308c\u3066\u3044\u308b Ring20 \u30b5\u30fc\u30d3\u30b9\u306e 10 \u306e\u3046\u3061 7 \u3064\u304c\u6709\u7528\u3067\u3042\u308a\u3001r(20) \u75c7\u5019\u7fa4\u306b\u5bfe\u51e6\u3059\u308b\u4e0a\u3067\u81ea\u5206\u305f\u3061\u306e\u751f\u6d3b\u306b\u30d7\u30e9\u30b9\u306e\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u308b\u3053\u3068\u306b\u540c\u610f\u3057\u307e\u3057\u305f\u3002\u534a\u6570\u5f31\u304c\u300110\u9805\u76ee\u4e2d2\u9805\u76ee\u304c\u751f\u6d3b\u306e\u8cea\u3092\u6539\u5584\u3059\u308b\u306e\u306b\u5f79\u7acb\u3064\u3053\u3068\u306b\u540c\u610f\u3057\u305f.\u3053\u306e\u7d50\u679c\u306f\u3001Ring20 \u304c\u63d0\u4f9b\u3059\u308b\u30b5\u30fc\u30d3\u30b9\u3068\u30b5\u30dd\u30fc\u30c8\u304c\u3001r(20) \u75c7\u5019\u7fa4\u306e\u60a3\u8005\u3068\u305d\u306e\u4ecb\u8b77\u8005\u304c\u65e5\u5e38\u751f\u6d3b\u306b\u5bfe\u51e6\u3059\u308b\u4e0a\u3067\u30d7\u30e9\u30b9\u306e\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002
\u3053\u306e\u7814\u7a76\u306f\u3001r(20)\u75c7\u5019\u7fa4\u3092\u6271\u3063\u3066\u3044\u308b\u4eba\u3005\u304c\u5c06\u6765\u306e\u7814\u7a76\u306b\u53c2\u52a0\u3057\u305f\u3044\u3068\u8003\u3048\u3066\u304a\u308a\u3001\u60a3\u8005\u4e3b\u5c0e\u306e\u7814\u7a76\u304c\u3053\u306e\u975e\u5e38\u306b\u307e\u308c\u306a\u72b6\u614b\u3067\u6709\u76ca\u3067\u3042\u308b\u3053\u3068\u3092\u793a\u3057\u3066\u3044\u307e\u3059.\u8981\u7d04\u3059\u308b\u3068\u3001Ring20 \u306e\u7814\u7a76\u306f\u3001r(20) \u75c7\u5019\u7fa4\u306b\u82e6\u3057\u3080\u4eba\u3005\u306b\u5229\u76ca\u3092\u3082\u305f\u3089\u3059\u3060\u3051\u3067\u306a\u304f\u3001\u60a3\u8005\u306e\u751f\u6d3b\u3092\u6539\u5584\u3057\u3001\u533b\u7642\u5c02\u9580\u5bb6\u3092\u6559\u80b2\u3059\u308b\u305f\u3081\u306b\u3001r(20) \u75c7\u5019\u7fa4\u306e\u3055\u3089\u306a\u308b\u7814\u7a76\u3068\u975e\u5e38\u306b\u5fc5\u8981\u306a\u3055\u3089\u306a\u308b\u7814\u7a76\u306b\u3068\u3063\u3066\u975e\u5e38\u306b\u91cd\u8981\u3067\u3059\u3002<\/p>

\u53c2\u8003\u6587\u732e<\/b>
Daber, RD, Conlin, LK, Leonard, LD, Canevini, MP, Vignoli, A., Hosain, S., Brown, LW, & Spinner, NB (2012).\u30ea\u30f3\u30b0\u67d3\u8272\u4f53 20. European Journal of Medical Genetics\u300155(5)\u3001381\u2013387\u3002 https:\/\/doi.org\/10.1016\/j.ejmg.2012.02.004
Donald, G.\u3001Allison, W.\u3001Archana, D.\u3001Laura, C.\u3001\u304a\u3088\u3073 Thomas F, H. (2020)\u3002\u74b0\u72b6\u67d3\u8272\u4f5320\u75c7\u5019\u7fa4\u306b\u304a\u3051\u308b\u30b1\u30c8\u30b8\u30a7\u30cb\u30c3\u30af\u98df\u4e8b\u7642\u6cd5\u306e\u5f79\u5272\u306e\u8a55\u4fa1\uff1a\u60a3\u8005\u4e3b\u5c0e\u306e\u30a2\u30d7\u30ed\u30fc\u30c1\u3002\u30d7\u30ed\u30af\u30a8\u30b9\u30c8\u30015(2)\u3001295\u2013300\u3002 https:\/\/doi.org\/10.1002\/epi4.12387
Elens, I., Vanrykel, K., De Waele, L., Jansen, K., Segeren, M., Van Paesschen, W., Ceulemans, B., Boel, M., Frijns, J.-P., Buyse\u3001G.\u3001\u304a\u3088\u3073Lagae\u3001L.\uff082012\uff09\u3002\u30ea\u30f3\u30b0\u67d3\u8272\u4f53 20 \u75c7\u5019\u7fa4: 6 \u4eba\u306e\u60a3\u8005\u306e\u96fb\u6c17\u81e8\u5e8a\u7684\u8aac\u660e\u3068\u6587\u732e\u306e\u30ec\u30d3\u30e5\u30fc\u3002\u3066\u3093\u304b\u3093\u3068\u884c\u52d5\u300123(4)\u3001409\u2013414\u3002 https:\/\/doi.org\/10.1016\/j.yebeh.2012.02.008
Giardino, D., Vignoli, A., Ballarati, L., Recalcati, MP, Russo, S., Camporeale, N., Marchi, M., Finelli, P., Accorsi, P., Giordano, L., La Briola, F., Chiesa, V., Canevini, MP, & Larizza, L. (2010).\u30ea\u30f3\u30b0 20 \u67d3\u8272\u4f53\u75c7\u5019\u7fa4\u306b\u7f79\u60a3\u3057\u305f 8 \u4eba\u306e\u60a3\u8005\u306e\u907a\u4f1d\u5b50\u8abf\u67fb\u3002 BMC Medical Genetics\u300111(1)\u3002 https:\/\/doi.org\/10.1186\/1471-2350-11-146
Peron, A., Catusi, I., Recalcati, MP, Calzari, L., Larizza, L., Vignoli, A., & Canevini, MP (2020).\u74b0\u72b6\u67d3\u8272\u4f53 20 \u75c7\u5019\u7fa4: \u907a\u4f1d\u5b66\u3001\u81e8\u5e8a\u7684\u7279\u5fb4\u3001\u304a\u3088\u3073\u91cd\u8907\u3059\u308b\u8868\u73fe\u578b\u3002\u795e\u7d4c\u5b66\u306e\u6700\u524d\u7dda\u300111\u3001613035. https:\/\/doi.org\/10.3389\/fneur.2020.613035
\u30ef\u30c8\u30bd\u30f3\u3001A. (2014)\u3002 Ring 20 \u306e\u7814\u7a76\u3068\u30b5\u30dd\u30fc\u30c8\u3002 Ring20 \u306e\u7814\u7a76\u3068\u30b5\u30dd\u30fc\u30c8 \u82f1\u56fd\u306e CIO\u3002 https:\/\/ring20researchsupport.co.uk\/<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>","protected":false},"excerpt":{"rendered":"

Ring20 (\u6148\u5584\u56e3\u4f53) \u306e\u6d3b\u52d5\u304c\u3069\u306e\u3088\u3046\u306a\u5f71\u97ff\u3092\u4e0e\u3048\u3066\u3044\u308b\u304b\u77e5\u308a\u305f\u3044\u3067\u3059\u304b?\u8aad\u3080\u2026<\/p>","protected":false},"author":3,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[17,84],"tags":[],"class_list":["post-9686","post","type-post","status-publish","format-standard","hentry","category-blog","category-news"],"yoast_head":"\nReviewing the Impact of Ring Chromosome 20 Syndrome - Ring20 Research and Support UK CIO<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ring20researchsupport.co.uk\/ja\/2022\/06\/impact_of_r20\/\" \/>\n<meta property=\"og:locale\" content=\"ja_JP\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Reviewing the Impact of Ring Chromosome 20 Syndrome - Ring20 Research and Support UK CIO\" \/>\n<meta property=\"og:description\" content=\"Want to know what impact the work of Ring20 (the charity) has? 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